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The dietary supplement Singularis Superior Diosmin Complex is a high-quality combination of active nutrients. It contains diosmin, hesperidin, vitamin C, and extracts from the rhizome of Rhuscus spinosus and black pepper. The product is available in the form of herbal capsules and is therefore suitable for vegans and vegetarians.
Diosmin and hesperidin are the subject of numerous scientific studies demonstrating their positive effects on the cardiovascular system (especially on the condition of the veins in the lower limbs). Among the active substances used to prevent chronic venous diseases, the purified flavonoid fraction of diosmin and hesperidin remains the most highly recommended remedy. [3]
The mentioned flavonoids also promote the control of blood sugar levels, lipid profiles, kidney function, liver enzymes, and antioxidant enzymes, and modulate the signaling pathways related to glucose uptake and insulin sensitivity, which are involved in the development of diabetes and its complications.
Due to the addition of vitamin C and black pepper extract, the product Singularis exhibits antioxidant activity [ID 2115]. It therefore supports the body in fighting oxidative stress, which causes cell dysfunction and leads to premature cell death.
Furthermore, the extract from black pepper supports the digestive system and has a positive effect on the liver [ID 2113]. It also supports the function of the nervous system [ID 2111] and contributes to maintaining the normal functions of the female reproductive system.
Ascorbic acid is also involved in collagen synthesis [ID 130]. Collagen is a protein that is the main building block of connective tissue, which is found, among other places, in blood vessels and is responsible for maintaining their elasticity.
In summary, Singularis Superior Diosmin Complex is a high-quality dietary supplement containing substances such as Diosmin, Hesperidin, Bioperin, and Vitamin C. The product from Singularis is characterized by its simple and natural composition. Thanks to the use of exclusively plant-based ingredients, it is also suitable for vegans and vegetarians.
1 Gandhi GR, Vasconcelos ABS, Wu DT, Li HB, Antony PJ, Li H, Geng F, Gurgel RQ, Narain N, Gan RY. Citrus Flavonoids as Promising Phytochemicals Targeting Diabetes and Related Complications: A Systematic Review of In Vitro and In Vivo Studies. Nutrients. 2020 Sep 23;12(10):2907. doi: 10.3390/nu12102907. PMID: 32977511; PMCID: PMC7598193.
2 Karetová D, Suchopár J, Bultas J. Diosmin/Hesperidin: a cooperating tandem, or is Diosmin decisive and Hesperidin only an inactive component? Vnitr Lek. 2020 Spring;66(2):97-103. English. PMID: 32942884.
3 Gavorník P, Dukát A, Gašpar Ľ, Gavorníková E. Present and future in the management of venous vascular diseases [Gegenwart und Zukunft in der Behandlung von venösen Gefäßerkrankungen]. Vnitr Lek. 2015 Feb;61(2):151-6. Czech. PMID: 25813260.
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